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Updated: 12 hours 57 min ago

AstraZeneca divests global rights to Movantik

Tue, 02/25/2020 - 13:00
AstraZeneca has agreed to sublicense its global rights to Movantik (naloxegol), excluding Europe, Canada and Israel, to RedHill Biopharma (RedHill). Movantik is a peripherally acting mu-opioid receptor antagonist (PAMORA) indicated for the treatment of opioid-induced constipation (OIC).

Regular walnut consumption linked to health and longevity in women

Tue, 02/25/2020 - 11:00
According to a new epidemiological study, women in their late 50s and early 60s who consumed at least two servings of walnuts per week had a greater likelihood of healthy aging compared to those who did not eat walnuts. After accounting for various factors that could impact health in older adults, such as education and physical activity, walnuts were the only nut associated with significantly better odds of healthy aging.

Clover and GSK announce research collaboration to evaluate coronavirus (COVID-19) vaccine candidate with pandemic adjuvant system

Mon, 02/24/2020 - 13:00
Clover Biopharmaceuticals, a China based global clinical-stage biotechnology company focused on developing novel and transformative biologic therapies, announced today that it has entered into a research collaboration with GSK for its protein-based coronavirus vaccine candidate (COVID-19 S-Trimer).

SMi's 3rd Annual Pharmaceutical Microbiology East Coast

Mon, 02/24/2020 - 11:00
29 - 30 April 2020, Boston, USA.
The pharmaceutical microbiology industry has seen many changes during the progression into the 21st century. With advances in rapid microbiological methods, revisions being made to regulations in the industry, enhanced knowledge of the human microbiome, and novel testing methods, this industry is ever expanding.

Cross-talk between enzymes that read and correct recipes in the cookbook of life

Fri, 02/21/2020 - 13:00
DNA is the hereditary material in humans, a unique cookbook of who we are. This is where you'll find the answer as to why you have your specific eye and hair colour, or perhaps why you sunburn easily. Imagine your DNA as a giant cookbook with thousands of recipes. These recipes are genes that have to be read every single day.

SMi's 22nd Annual Superbugs & Superdrugs Conference 2020

Fri, 02/21/2020 - 11:00
30 - 31 May 2020, London, UK.
As one of the most impactful pharmaceuticals for maintaining public health, antibiotics have been around since early 20th century and have since shown a need for significant progress in recent years. This is mainly due to its broad and indiscriminate use which has slowly given birth to multi- to extensively-drug resistant bacteria rendering our current last-resort antibiotic arsenal, including colistin, carbapenems, 3rd and 4th generation cephalosporins, useless.

Research shows new drug helps to preserve brain cells for a time after stroke

Thu, 02/20/2020 - 13:00
After 50 years of research and the testing of over 1,000 drugs, there is new hope for preserving brain cells for a time after stroke. Treating acute ischemic stroke patients with an experimental neuroprotective drug, combined with a surgical procedure to remove the clot improves outcomes as shown by clinical trial results published today in The Lancet.

FDA approves GSK's Voltaren Arthritis Pain for over-the-counter use in the United States

Thu, 02/20/2020 - 11:00
GlaxoSmithKline (LSE/NYSE: GSK) announced that the U.S. Food and Drug Administration (FDA) has approved Voltaren Arthritis Pain (diclofenac sodium topical gel, 1% (NSAID)- arthritis pain reliever) as an over-the-counter (OTC) product for the temporary relief of arthritis pain in the hand, wrist, elbow, foot, ankle or knee in adults (18 years and older).

Breakthrough in coronavirus research results in new map to support vaccine design

Wed, 02/19/2020 - 13:00
Researchers from The University of Texas at Austin and the National Institutes of Health have made a critical breakthrough toward developing a vaccine for the 2019 novel coronavirus by creating the first 3D atomic scale map of the part of the virus that attaches to and infects human cells.

FDA grants priority review to Roche's Tecentriq monotherapy as first-line treatment of certain people with advanced non-small cell lung cancer

Wed, 02/19/2020 - 11:00
Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced that the US Food and Drug Administration (FDA) has accepted the company's supplemental Biologics License Application (sBLA) and granted Priority Review for Tecentriq® (atezolizumab) as a first-line (initial) monotherapy for people with advanced non-squamous and squamous non-small cell lung cancer (NSCLC) without

Predicting immunotherapy success

Tue, 02/18/2020 - 13:00
One of the frustrations with anti-cancer therapy is that no one drug fits all: Most work well in some people but have little effect in other patients with the same type of cancer. This is as true of the newer immunotherapy treatments as it is of older types of chemotherapy. Weizmann Institute of Science researchers have now identified new markers that can help predict which patients have a better chance for a positive response to immunotherapy treatments.

FDA takes action with Indian Government to protect consumers from illicit medical products

Tue, 02/18/2020 - 11:00
The U.S. Food and Drug Administration today announced that its first bilateral enforcement operation with the Government of India, stopped approximately 500 shipments of illicit, and potentially dangerous, unapproved prescription drugs and combination medical devices from reaching American consumers over the course of an operation that took place in January.

Researchers challenge new guidelines on aspirin in primary prevention

Mon, 02/17/2020 - 13:00
The most recent guidelines for primary prevention recommend aspirin use for individuals ages 40 to 70 years who are at higher risk of a first cardiovascular event, but not for those over 70. Yet, people over 70 are at increasingly higher risks of cardiovascular events than those under 70.

SMi Presents the 3rd Annual Conference: Injectable Drug Delivery 2020

Mon, 02/17/2020 - 11:00
13 - 14 May 2020, London, UK.
SMi Group is pleased to announce the third annual Injectable Drug Delivery conference, which will be held in London. Part of Europe's leading Injectable conference series, Injectable Drug Delivery will assess innovations in drug product formulation and biologics, innovations in device design, quality management and connectivity for enhanced subcutaneous delivery.

SMi Presentsthe 3rd Annual Conference: Injectable Drug Delivery 2020

Mon, 02/17/2020 - 11:00
13 - 14 May 2020, London, UK.
SMi Group is pleased to announce the third annual Injectable Drug Delivery conference, which will be held in London. Part of Europe's leading Injectable conference series, Injectable Drug Delivery will assess innovations in drug product formulation and biologics, innovations in device design, quality management and connectivity for enhanced subcutaneous delivery.

Double success for University drug resistance research

Fri, 02/14/2020 - 11:00
Swansea University research into the threat posed by antifungal drug resistance has been highlighted in two prestigious international journals. Fungal disease now kills more people than malaria or TB and the Centre for Disease Control in the USA recognises emergence of multi-drug resistance in fungi as a high level threat.

Can bilingualism protect the brain even with early stages of dementia?

Thu, 02/13/2020 - 13:00
A study by York University psychology researchers provides new evidence that bilingualism can delay symptoms of dementia. Alzheimer's disease is the most common form of dementia, making up 60 to 70 per cent of dementia cases. Of all activities with neuroplastic benefits, language use is the most sustained, consuming the largest proportion of time within a day. It also activates regions across the entire brain.

Remdesivir prevents MERS coronavirus disease in monkeys

Thu, 02/13/2020 - 11:00
The experimental antiviral remdesivir successfully prevented disease in rhesus macaques infected with Middle East respiratory syndrome coronavirus (MERS-CoV), according to a new study from National Institutes of Health scientists. Remdesivir prevented disease when administered before infection and improved the condition of macaques when given after the animals already were infected.

Novartis announces MET inhibitor capmatinib (INC280), the first potential treatment for METex14 mutated advanced non-small cell lung cancer, granted priority FDA review

Wed, 02/12/2020 - 13:00
Novartis announced that the US Food and Drug Administration (FDA) accepted and granted Priority Review to capmatinib’s (INC280) New Drug Application (NDA). Capmatinib is a MET inhibitor being evaluated as a treatment for first-line and previously treated patients with locally advanced or metastatic MET exon 14 skipping (METex14) mutated non-small cell lung cancer (NSCLC)(1).

Scientists find ally in fight against brain tumors: Ebola

Wed, 02/12/2020 - 11:00
Glioblastomas are relentless, hard-to-treat, and often lethal brain tumors. Yale scientists have enlisted a most unlikely ally in efforts to treat this form of cancer - elements of the Ebola virus.

"The irony is that one of the world's deadliest viruses may be useful in treating one of the deadliest of brain cancers," said Yale's Anthony van den Pol, professor of neurosurgery, who describes the Yale efforts Feb. 12 in the Journal of Virology.