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FDA approves first oral GLP-1 treatment for type 2 diabetes

World Pharma News - Fri, 09/20/2019 - 12:00
The U.S. Food and Drug Administration today approved Rybelsus (semaglutide) oral tablets to improve control of blood sugar in adult patients with type 2 diabetes, along with diet and exercise. Rybelsus is the first glucagon-like peptide (GLP-1) receptor protein treatment approved for use in the United States that does not need to be injected.

Dengue virus becoming resistant to vaccines and therapeutics due to mutations in specific protein

World Pharma News - Fri, 09/20/2019 - 10:00
Researchers from Duke-NUS Medical School (DukeNUS), in collaboration with the Agency for Science, Technology and Research (A*STAR)'s Bioinformatics Institute (BII), and the University of Texas Medical Branch (UTMB), USA, have discovered that the dengue virus changes its shape through mutations in Envelope (E) protein to evade vaccines and therapeutics.

Should You Work with a Coach to Enhance Your Life Sciences Career?

Biospace news - Fri, 09/20/2019 - 02:00
Just what is a career coach? These practitioners have been compared to personal trainers for your life, your champion, cheerleader, advocate, partner and sounding board.

Alzheimer’s Disease Insight Report: Current Therapies, Drug Pipeline and Outlook

Biospace news - Fri, 09/20/2019 - 02:00
50 million people worldwide live with symptomatic Alzheimer's, which has no cure. In honor of September 21st being World Alzheimer's Day, we evaluated the current therapies, drugs in the pipeline and disease outlook.

New Data Shows Long-Term Benefits of Zolgensma in SMA Patients

Biospace news - Fri, 09/20/2019 - 02:00
While the approval of AveXis’ gene therapy for spinal muscular atrophy has been tainted by the revelation of early data manipulation, the Novartis subsidiary presented some long-term data at a conference that backs up the treatment’s efficacy.

BioSpace Movers & Shakers, Sept. 20

Biospace news - Fri, 09/20/2019 - 02:00
Biotech and pharma companies from across the globe strengthen their leadership teams and boards of directors with this week's appointments.

Allogene Partnering with Stanford to Develop Better CAR-T Therapies

Biospace news - Fri, 09/20/2019 - 02:00
South San Francisco-based Allogene Therapeutics inked a research collaboration deal with Stanford University to work on a novel nucleic acid delivery system for CAR-T therapy.

Research Roundup: Alzheimer’s Memory Loss Reversed and More

Biospace news - Fri, 09/20/2019 - 02:00
Every week there are numerous scientific studies published. Here’s a look at some of the more interesting ones.

Rheumatoid Arthritis Drug May Help Repair Heart After Heart Attacks

Biospace news - Fri, 09/20/2019 - 02:00
Researchers at Vanderbilt University recently studied the inflammation phase after heart attacks and identified a protein, cadherin-11, that is significantly involved in the inflammation in cardiac fibrosis.

Novo's Tresiba Misses Comparison Mark to Sanofi's Toujeo

Biospace news - Fri, 09/20/2019 - 02:00
While the Danish drugmaker’s Tresiba (insulin degludec) didn’t fare as well as hoped in the head-to-head trial, Novo Nordisk was quick to point out that Tresiba showed an overall lower risk of hypoglycemia compared to Toujeo.

Sponsored | Now & Next with Jubilant Biosys: The Evolution of BioPharma, Drug Discovery, Developm...

Biospace news - Fri, 09/20/2019 - 02:00
Saurabh Kapure, Vice President, Business Development, USA for Jubilant Biosys, recently sat down with Siegfried Reich, Ph.D. Co-founder and Senior Vice President, Research, at eFFECTOR Therapeutics.

AstraZeneca amends collaboration with Ironwood for Linzess in China

World Pharma News - Thu, 09/19/2019 - 10:00
AstraZeneca has amended its collaboration agreement with Ironwood Pharmaceuticals, Inc. (Ironwood) in China mainland, China Hong Kong and China Macau for Linzess (linaclotide), a first-in-class new treatment for patients with irritable bowel syndrome with constipation (IBS-C).

How to Relocate for Your Life Sciences Career

Biospace news - Thu, 09/19/2019 - 02:00
Here are the keys to a smooth long distance job search. Follow these simple guidelines to avoid many of the stresses of job hunting from a distance.

Speaker Pelosi Unveils Plan to Negotiate Lower Drug Prices

Biospace news - Thu, 09/19/2019 - 02:00
House Speaker Nancy Pelosi unveiled her plan to lower the prices on up to 250 prescription drugs covered by government-backed plans such as Medicare.

BioSpace Global Roundup, Sept. 19

Biospace news - Thu, 09/19/2019 - 02:00
Biotech and pharma companies from across the globe share updates on company business and pipelines.

Aimmune Eyes 2020 Approval of Peanut Allergy Treatment

Biospace news - Thu, 09/19/2019 - 02:00
Aimmune’s peanut allergy treatment is one-step closer to approval following strong support from the Allergenic Products Advisory Committee, which overwhelmingly recommended approval of Palforzia, the proposed trade name of the investigational oral treatment, AR101.

Researchers Develop New Class of Lung Cancer Drugs

Biospace news - Thu, 09/19/2019 - 02:00
Working with a new class of cancer drugs called G12C KRAS inhibitors, researchers at the Francis Crick Institute and The Institute of Cancer Research (ICR), London, developed drug combinations to stay ahead of drug resistant tumors.

4 Ways Employee Recognition Can Decrease Turnover

Biospace news - Thu, 09/19/2019 - 02:00
The amount of recognition workers receive can be linked to employee turnover rates.

Study Raises Concern Over Risk of Bias in EMA-Approved Cancer Trials

Biospace news - Thu, 09/19/2019 - 02:00
A new study shows that approximately half of clinical trials that supported approvals for new cancer drugs in Europe were judged to be at high risk of bias, meaning that some treatment effects might have been exaggerated.

Novartis Releases Interim Data from Zolgensma Trial

Biospace news - Thu, 09/19/2019 - 02:00
AveXis presented new interim data from the Phase III SPR1NT trial of Zolgensma (onasemnogene abeparvovec-xioi) in spinal muscular atrophy (SMA) Type 1.