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Huntington's Disease Continues to Baffle Biopharma

Biospace news - Thu, 11/17/2022 - 02:00
Huntington’s disease might just top the list of intractable neurodegenerative diseases. BioSpace spoke with the field's foremost experts about the challenges and how to overcome them.

Regeneron, CytomX Ink Potentially $2B Bispecific Immunotherapy Deal

Biospace news - Thu, 11/17/2022 - 02:00
Regeneron and CytomX Therapeutics inked a deal valued at up to $2 billion to develop next-generation bispecific immunotherapies for cancer, the companies announced Thursday.

In Latest PARP Probe, FDA Asks Clovis to Limit Rubraca’s Label

Biospace news - Thu, 11/17/2022 - 02:00
​​​​​​​The FDA has requested that Clovis Oncology limit the indication of its PARP inhibitor Rubraca as second-line maintenance therapy in recurrent ovarian cancer.

Newly-Launched Normunity Becomes Alloy's Latest Partner in IO Deal

Biospace news - Thu, 11/17/2022 - 02:00
Alloy Therapeutics inked an antibody discovery deal with Normunity Thursday to advance the latter’s immune normalizers, antibody therapies that boost the body’s natural immune system to fight cancer.

Ardelyx’s CKD Drug Clears FDA Adcomm Hurdle with 9-4 Vote

Biospace news - Thu, 11/17/2022 - 02:00
Ardelyx has moved one step closer to the possible approval of its experimental chronic kidney disease drug tenapanor following a favorable 9-4 vote from an FDA advisory committee.

Three Influential Women in Biopharma Explain How to Break the Executive Barrier

Biospace news - Thu, 11/17/2022 - 02:00
According to a BIO report, less than a third of executive team members are women. BioSpace spoke with three influential women in biopharma to get their advice on breaking the executive barrier.

Machine learning can help predict patient response to cancer immunotherapy

World Pharma News - Wed, 11/16/2022 - 11:00
Predicting which patients will respond well to treatment is a quandary that has plagued the field of cancer immunotherapy for more than four decades. Now, researchers at the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy are one step closer to solving that problem.

Kinarus Therapeutics Engages Great Health Companion Group to Explore Partnerships in China Kinarus Therapeutics Holding AG announced that it has engaged Great Health Companion Group Ltd, a subsidiary of Hakim Unique Group, a global conglomerate from China

Biospace news - Wed, 11/16/2022 - 02:00
Surrozen announced it paused its Phase I study in Crohn’s disease and ulcerative colitis as several healthy participants showed increased levels of liver enzymes.

Sanofi and GSK's next-generation COVID-19 booster vaccine VidPrevtyn® Beta approved by the European Commission

World Pharma News - Tue, 11/15/2022 - 11:00
After the European Medicines Agency's Committee for Medicinal Products for Human Use (CHMP) adopted a positive opinion for VidPrevtyn® Beta, the vaccine was approved by the European Commission, as a booster for the prevention of COVID-19 in adults 18 years of age and older.

Neoleukin Drops de Novo Protein Therapeutic, Slashes Workforce - Updated

Biospace news - Tue, 11/15/2022 - 02:00
Neoleukin Therapeutics plans to slash its workforce by about 40% and drop NL-201, a de novo IL-2/IL-15 agonist currently in Phase I, according to its third-quarter report.

Beam Enrolls Trial's First Patient in "Step Forward" for Base Editing

Biospace news - Tue, 11/15/2022 - 02:00
Beam Therapeutics has enrolled the first patient in a Phase I/II trial studying a gene therapy leveraging base editing in adults with severe sickle cell disease.

Roche Doubles Down on Jnana's RAPID Platform in $2B Deal (Updated)

Biospace news - Tue, 11/15/2022 - 02:00
Jnana Therapeutics forged its second small molecule discovery and development collaboration and licensing agreement with Roche valued at up to $2 billion.

Good Therapeutics’ Offshoot Bonum Launches with $93 Million in Series A (Updated)

Biospace news - Tue, 11/15/2022 - 02:00
Two months after selling an immuno-oncology platform developed by Good Therapeutics to Roche, Bonum Therapeutics launched Tuesday with $93 million in Series A financing.

FDA Approves First-Ever ADC​​​​​​​ in Platinum-Resistant Ovarian Cancer (Updated)

Biospace news - Tue, 11/15/2022 - 02:00
ImmunoGen's Elahere was approved Monday under the FDA's accelerated pathway for patients who have received one to three previous lines of systemic therapy.

Pittsburgh Sees Transformation into Life Sciences Hotbed

Biospace news - Tue, 11/15/2022 - 02:00
A former steel industry giant, the 21st century Pittsburgh is a global life sciences hub, transforming research, technology and startups into a thriving center for innovation.

Acrivon Becomes Biotech's 20th IPO of 2022 with $99M Offering

Biospace news - Tue, 11/15/2022 - 02:00
​​​​​​​Acrivon Therapeutics announced the pricing of its initial public offering Tuesday, putting all of its 7,550,000 shares of common stock up for sale for $12.50 apiece.

Junshi Biosciences Announces Submission of a Marketing Authorization Application to the European Medicines Agency for Toripalimab Shanghai Junshi Biosciences Co., Ltd (“Junshi Biosciences”, HKEX: 1877; SSE: 688180), a leading innovation-driven biopharmace

Biospace news - Tue, 11/15/2022 - 02:00
The FDA raised doubts about the future of Ardelyx's experimental chronic kidney disease drug tenapanor in briefing documents released ahead of a Wednesday advisory committee meeting.

Best Places to Work in Biopharma 2023 Report Reveals Most Sought-After Employers

Biospace news - Tue, 11/15/2022 - 02:00
BioSpace's 2023 “Best Places to Work,” highlights innovative companies with a positive workplace culture, flexibility and strong leadership.

New drug shows promise for fighting both COVID-19 and cancer

World Pharma News - Mon, 11/14/2022 - 11:00
While vaccination can provide life-saving protection against COVID-19, scientists are still searching for ways to treat severe infections, including in people who cannot get vaccinated or in the event that dangerous new strains of the virus arise that could bypass vaccine protection.

Biogen-Lilly Solidly in the Lead After Roche's Alzheimer's Drug Misses in Phase III

Biospace news - Mon, 11/14/2022 - 02:00
Roche announced its investigational antibody gantenerumab failed to meet the primary endpoints in GRADUATE I and II - two Phase III studies in Alzheimer's disease.