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Money on the Move: ReCode, MiroBio & More Target Technology

Biospace news - Wed, 06/29/2022 - 02:00
This week money went towards more advanced rounds of financing for drugs and technology that have already shown a lot of promises.

Generian, Mitobridge (Astellas) Partner to Expand Playbook of what is Druggable

Biospace news - Wed, 06/29/2022 - 02:00
Generian and Mitobridge, a wholly-owned subsidiary of Astellas Pharma, announced a collaboration to discover and develop novel small molecules for undruggable therapeutic targets.

Beyond Increments: Black Perspectives on Representation in the Life Sciences

Biospace news - Wed, 06/29/2022 - 02:00
BioSpace spoke with several Black individuals working within the life sciences to get their thoughts on the current representative disconnect and what they believe can be done to fix it.

Cannabis-Derived MS Treatment Disappoints in Phase III Trial

Biospace news - Wed, 06/29/2022 - 02:00
The Phase III study of Jazz Pharmaceuticals cannabis-derived MS Sativex failed to achieve the primary endpoint of an improvement in muscle tone in patients.

FDA Advisory Committee Calls For Updated COVID-19 Boosters to Quell Omicron

Biospace news - Wed, 06/29/2022 - 02:00
​​​​​​​Voting 19-2, the Vaccines and Related Biological Products Advisory Committee favored redesigning booster shots to include the coronavirus’ Omicron variant.

ARCH Defies Biotech Market Slowdown with New $3B Fund

Biospace news - Wed, 06/29/2022 - 02:00
"Science doesn’t care what markets are doing, and science moves forward," ARCH Co-founder and Managing Director Robert Nelsen said in a statement.

Icosavax Preps IND Application for RSV Vaccine Following Positive Data

Biospace news - Wed, 06/29/2022 - 02:00
Icosavax posted positive topline interim data from its Phase I/Ib trial of IVX-121, its candidate virus-like particle vaccine against the respiratory syncytial virus in young and older adults.

Researchers Discover Candida auris Can Reproduce Sexually

Biospace news - Wed, 06/29/2022 - 02:00
A deadly fungus–Candida auris (C. auris)–has shaken up the biological world with its ability to reproduce sexually. What can be its dangers and what are the next steps? Know it all here.

New Research Explores the Role of Oxygen in Cancer Growth

Biospace news - Wed, 06/29/2022 - 02:00
New research by investigators at Columbia University and MIT describes how cancer cells often depend upon the importation of fat for continued growth and division.

How to Write an Effective Cover Letter for a Research Scientist Job

Biospace news - Wed, 06/29/2022 - 02:00
This article offers a template with examples of an effective cover letter for a research scientist job. Let's explore some tips to help you write your own.

New Novartis extension phase data show nearly 80% of RMS patients treated with Kesimpta® (ofatumumab) had no evidence of disease activity (NEDA-3)

World Pharma News - Tue, 06/28/2022 - 10:00
Novartis today announced new data from the Phase 3 ASCLEPIOS I/II trials and the ALITHIOS open-label extension showing continuous treatment with Kesimpta® (ofatumumab) significantly increased the odds of achieving no evidence of disease activity (NEDA-3) versus switching from teriflunomide(1). These data were presented at the European Academy of Neurology (EAN) Annual Meeting being held in Vienna, Austria and virtually on June 25-28, 2022.

Novartis Reveals Restructure will Cost up to 8,000 Jobs

Biospace news - Tue, 06/28/2022 - 02:00
Swiss biopharma giant Novartis plans to cut up to 8,000 jobs in hopes of saving at least $1 billion by 2024.

Pfizer, Roivant Unveil Priovant with High Potential TYK2/JAK1 Inhibitor

Biospace news - Tue, 06/28/2022 - 02:00
Pfizer and Roivant unveiled Priovant Therapeutics to develop and market new therapies for a wide range of autoimmune diseases with high mortality and morbidity rates.

Astellas and Sutro Unite to Overcome Checkpoint Inhibitor Limitations with iADCs

Biospace news - Tue, 06/28/2022 - 02:00
Astellas Pharma and Sutro Biopharma inked a global collaboration and licensing deal to work to discover and develop novel immunostimulatory antibody-drug conjugates.

Boehringer Expands BiomX IBD Biomarker Collab, Shutters Crohn's Trial

Biospace news - Tue, 06/28/2022 - 02:00
Boehringer and BiomX intend to use the discovery platform to identify biomarkers for a pathogenic bacterium thought to be associated with IBD.

Roivant Reduces Pipeline by Several Programs Across Vants

Biospace news - Tue, 06/28/2022 - 02:00
Roivant Sciences announced it has discontinued development of several assets following a pipeline reprioritization.

New Study: COVID-19 May Cause or Accelerate Neurological Diseases

Biospace news - Tue, 06/28/2022 - 02:00
Danish researchers published a study suggesting that COVID-19 increases the risk of neurodegenerative diseases such as Alzheimer’s and Parkinson’s disease.

Ascletis Embarks on Mid-stage Study of Potentially Functional Cure for HIV

Biospace news - Tue, 06/28/2022 - 02:00
Ascletis has commenced its Phase II trial in China for its candidate drug ASC22 alongside anti-retroviral therapy for the functional cure and immune restoration of HIV-1 infection.

Innovative Treatments on the Horizon for Anxiety Disorder

Biospace news - Tue, 06/28/2022 - 02:00
MindMed, Scripps Research, Cingulate Therapeutics and the University of Pennsylvania discuss innovative treatments on the horizon for the treatment of anxiety disorder.

Spero Searching for Way Forward after FDA Rejects cUTI Drug

Biospace news - Tue, 06/28/2022 - 02:00
Spero Therapeutics received a Complete Response Letter from the U.S. Food and Drug Administration for its complicated urinary tract infection therapy, tebipenem HBr oral tablets.