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Roche Inks Potential $1.8B Deal With Ascidian to Develop RNA Exon Therapies

Biospace news - Tue, 06/18/2024 - 02:00
Roche Inks Potential $1.8B Deal With Ascidian to Develop RNA Exon Therapies 6/18/2024

Decheng Capital Eyes $700M Raise for Fifth Life Sciences Fund as VC Heats Up

Biospace news - Tue, 06/18/2024 - 02:00
Decheng Capital Eyes $700M Raise for Fifth Life Sciences Fund as VC Heats Up 6/18/2024

Nano-immunotherapy developed to improve lung cancer treatment

World Pharma News - Mon, 06/17/2024 - 10:00
Researchers at Brigham and Women's Hospital, a founding member of the Mass General Brigham healthcare system, have developed a new nanomedicine therapy that delivers anticancer drugs to lung cancer cells and enhances the immune system's ability to fight cancer. The team showed promising results for the new therapy in cancer cells in the lab and in mouse lung tumor models, with potential applications for improving care and outcomes for patients with tumors that have failed to respond to traditional immunotherapy. Their findings are published in Science Advances.

FDA Slaps BioNTech-MediLink ADC With Partial Clinical Hold Due to ‘Significant Risk of Illness’

Biospace news - Mon, 06/17/2024 - 02:00
FDA Slaps BioNTech-MediLink ADC With Partial Clinical Hold Due to ‘Significant Risk of Illness’ 6/17/2024

Takeda’s Epilepsy Drug Stumbles in Back-to-Back Phase III Rare Disease Failures

Biospace news - Mon, 06/17/2024 - 02:00
Takeda’s Epilepsy Drug Stumbles in Back-to-Back Phase III Rare Disease Failures 6/17/2024

Gilead’s Magrolimab Ineffective, Linked to Increase Risk of Death in MDS Patients

Biospace news - Mon, 06/17/2024 - 02:00
Gilead’s Magrolimab Ineffective, Linked to Increase Risk of Death in MDS Patients 6/17/2024

AstraZeneca’s Imfinzi Gets FDA Approval for Treating Endometrial Cancer

Biospace news - Mon, 06/17/2024 - 02:00
AstraZeneca’s Imfinzi Gets FDA Approval for Treating Endometrial Cancer 6/17/2024

Novo Nordisk CEO Agrees to Testify at Senate Hearing After Sanders’ Subpoena Threat

Biospace news - Mon, 06/17/2024 - 02:00
Novo Nordisk CEO Agrees to Testify at Senate Hearing After Sanders’ Subpoena Threat 6/17/2024

J&J’s $6.5B Momenta Buy Pays Off With Phase II Sjögren’s Disease Win

Biospace news - Mon, 06/17/2024 - 02:00
J&J’s $6.5B Momenta Buy Pays Off With Phase II Sjögren’s Disease Win 6/17/2024

Genetic Therapies Show Early Promise in Treating Obesity

Biospace news - Mon, 06/17/2024 - 02:00
Genetic Therapies Show Early Promise in Treating Obesity 6/17/2024

AI Enables Individualized Cancer Vaccines

Biospace news - Mon, 06/17/2024 - 02:00
AI Enables Individualized Cancer Vaccines 6/17/2024

FDA Action Alert: Merck, BMS, Sarepta and More

Biospace news - Mon, 06/17/2024 - 02:00
FDA Action Alert: Merck, BMS, Sarepta and More 6/17/2024

Opinion: Regulatory Flexibility Can Accelerate Rare Disease Drug Development

Biospace news - Mon, 06/17/2024 - 02:00
Opinion: Regulatory Flexibility Can Accelerate Rare Disease Drug Development 6/17/2024

Obesity-cancer connection discovery suggests strategies for improving immunotherapy

World Pharma News - Fri, 06/14/2024 - 10:00
Immune system cells called macrophages play an unexpected role in the complicated connection between obesity and cancer, a Vanderbilt University Medical Center-led research team has discovered.

Obesity increases the frequency of macrophages in tumors and induces their expression of the immune checkpoint protein PD-1 - a target of cancer immunotherapies. The findings, published June 12 in the journal Nature, provide a mechanistic explanation for how obesity can contribute to both increased cancer risk and enhanced responses to immunotherapy.

Telix Abandons IPO Plans at Last Minute, Cites ‘Current Market Conditions’

Biospace news - Fri, 06/14/2024 - 02:00
Telix Abandons IPO Plans at Last Minute, Cites ‘Current Market Conditions’ 6/14/2024

J.P. Morgan Raises Over $500M for First Biotech Venture Capital Fund

Biospace news - Fri, 06/14/2024 - 02:00
J.P. Morgan Raises Over $500M for First Biotech Venture Capital Fund 6/14/2024

SCOTUS Upholds Access to Abortion Pill, Pharma Industry Applauds Court’s Ruling

Biospace news - Fri, 06/14/2024 - 02:00
SCOTUS Upholds Access to Abortion Pill, Pharma Industry Applauds Court’s Ruling 6/14/2024

GLP-1 Global Obesity Market to Reach $111B by 2033, Despite Headwinds: GlobalData

Biospace news - Fri, 06/14/2024 - 02:00
GLP-1 Global Obesity Market to Reach $111B by 2033, Despite Headwinds: GlobalData 6/14/2024

With Donanemab on the Cusp of Approval, Proper Alzheimer’s Diagnosis Is Urgent

Biospace news - Fri, 06/14/2024 - 02:00
With Donanemab on the Cusp of Approval, Proper Alzheimer’s Diagnosis Is Urgent 6/14/2024

BMS’ Augtyro Wins FDA Accelerated Approval for NTRK-Positive Solid Tumors

Biospace news - Fri, 06/14/2024 - 02:00
BMS’ Augtyro Wins FDA Accelerated Approval for NTRK-Positive Solid Tumors 6/14/2024