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How to Get the Most Out of Your Recruiter Relationship

Biospace news - Mon, 12/12/2022 - 02:00
Teaming up with a recruiter can be a smart move in a tight job market or for job seekers looking for a specialized role. To help you in your job search, we've outlined how to get the best out of recruiters.

Bayer launches industry-first public database listing company's science collaborations and partnerships in the U.S.

World Pharma News - Fri, 12/09/2022 - 11:00
Bayer has announced the U.S. launch of the Bayer Science Collaboration Explorer (BSCE) as part of its ongoing efforts to enhance public trust in scientific innovations, processes, and R&D activities. The Explorer is a publicly accessible database where Bayer shares information on its science collaborations and new contracts with universities, public research institutions, and individuals.

Autolus Meets Phase II Acute Lymphoblastic Leukemia Endpoint

Biospace news - Fri, 12/09/2022 - 02:00
Autolus Therapeutics is calling the Phase II FELIX trial, assessing its next-generation CAR-T therapy obe-cel for leukemia, a win after an interim analysis revealed an overall remission rate of 70%.

ImmunoGen and Gilead Team Up to Target AML

Biospace news - Fri, 12/09/2022 - 02:00
ImmunoGen entered into a clinical collaboration deal with Gilead Sciences Friday to evaluate the safety and efficacy of two drugs that, when used in concert, have the potential to treat AML.

Setting the Stage for ASH 2022

Biospace news - Fri, 12/09/2022 - 02:00
At ASH 2022, established hematology leaders like AstraZeneca, Janssen and Merck will showcase new data, and new players like Vega Therapeutics will launch new programs.

With Two Wins at SABCS, AstraZeneca Continues Breast Cancer Rally

Biospace news - Fri, 12/09/2022 - 02:00
​​​​​​​AstraZeneca posted two mid-stage wins at the 2022 San Antonio Breast Cancer Symposium on Thursday, touting the efficacy of capivasertib and camizestrant against breast cancer.

UCB Reports Positive Pivotal for New Approach to Hidradenitis Suppurativa (Updated)

Biospace news - Fri, 12/09/2022 - 02:00
UCB shared positive top-line results Friday from two Phase III studies of bimekizumab for adults with moderate to severe hidradenitis suppurativa.

Structural studies offer "how-to" guide for designing cancer drugs

World Pharma News - Thu, 12/08/2022 - 13:00
To design drugs that stall the growth of aggressive cancers, it helps to know the structures of the proteins that are revving the cancers' engines.

In a series of three papers published in Proceedings of the National Academy of Sciences, Scripps Research scientists have illuminated the three-dimensional structure of phosphoinositide 3-kinase alpha (PI3Kα), a protein often mutated in cancer cells.

CPHI Frankfurt returns to pre-pandemic strength as pharma industry booms again

World Pharma News - Thu, 12/08/2022 - 11:00
24 - 26 October, 2023, Barcelona, Spain.
The global pharma industry was out in full force at CPHI Frankfurt in November with 40,405 executives from 167 countries visiting the 2022 edition of the world-leading pharma industry tradeshow, a huge 75% increase over the number of attendees in 2021. Final visitor numbers will be confirmed by independent auditors ABC in early 2023.

Novartis Secures Second Phase III PNH Win in as Many Months

Biospace news - Thu, 12/08/2022 - 02:00
Novartis reported Thursday that a Phase III trial of iptacopan met its primary endpoint in paroxysmal nocturnal hemoglobinuria (PNH) - the company's second win in this indication in as many months.

‘Dramatic’ Placebo Effect Trips Relmada’s MDD Hopeful for the Second Time

Biospace news - Thu, 12/08/2022 - 02:00
Relmada's investigational NDMA receptor channel blocker, REL-1017, failed to meet its primary endpoint in major depressive disorder in the Phase III RELIANCE I trial.

Dantari Debuts with $47M to Make Better ADCs

Biospace news - Thu, 12/08/2022 - 02:00
With $47 million in hand, Dantari launched Thursday to advance its Targeted High-capacity Drug Conjugate technology – its take on an antibody-drug conjugate - for solid tumors.

Sanofi Backs Out of Revolution Partnership in Latest Cancer Cull

Biospace news - Thu, 12/08/2022 - 02:00
Sanofi has terminated its global development and commercialization pact with Revolution Medicines, Inc. for their SHP2 inhibitor drug candidate,

Psychedelic Medicine Takes Another Step Forward with Compass’ Twin Updates

Biospace news - Thu, 12/08/2022 - 02:00
Compass' twin clinical updates regarding its lead candidate spotlight the promise of psychedelic medicine.

Instil Bio Trashes a TIL Therapy, Cuts 60% of Staff

Biospace news - Thu, 12/08/2022 - 02:00
Instil Bio is discontinuing the development of its unmodified tumor-infiltrating lymphocyte (TIL) therapeutic, ITIL-168, and laying off 60% of its staff.

How to Cope with Setbacks and Stay Positive in an Unpredictable Industry

Biospace news - Thu, 12/08/2022 - 02:00
Those who work in the biopharma industry often see more setbacks than successes. To understand how to overcome failures, BioSpace spoke with two experts on coping with setbacks and staying positive.

New receptor "decoy" drug neutralizes COVID-19 virus and its variants

World Pharma News - Wed, 12/07/2022 - 11:00
Scientists at Dana-Farber Cancer Institute have developed a drug that potently neutralizes SARS-CoV-2, the COVID-19 coronavirus, and is equally effective against the Omicron variant and every other tested variant. The drug is designed in such a way that natural selection to maintain infectiousness of the virus should also maintain the drug’s activity against future variants.

Pfizer and Clear Creek Bio to collaborate on a research program targeting SARS-CoV-2 papain-like protease

World Pharma News - Tue, 12/06/2022 - 11:00
Pfizer Inc. (NYSE: PFE) and Clear Creek Bio, Inc. today announced a research collaboration and exclusive license agreement to advance the discovery and development of potential inhibitors of the SARS-CoV-2 papain-like protease (PLpro) for the oral treatment of COVID-19. PLpro is an essential enzyme, which, along with the main protease (Mpro), plays an important role in viral replication.

Mirati's KRAS Inhibitor Demonstrates Encouraging Clinical Profile in Latest Data Drop (Updated)

Biospace news - Tue, 12/06/2022 - 02:00
Mirati's adagrasib demonstrated a solid safety profile in new data released Monday. Despite this, the company's stock fell 8% in after-hours trading.