The program, called TopoFormer, was developed by an interdisciplinary team led by Guowei Wei, a Michigan State University Research Foundation Professor in the Department of Mathematics. TopoFormer translates three-dimensional information about molecules into data that typical AI-based drug-interaction models can use, expanding those models' abilities to predict how effective a drug might be.
EMBL Hamburg's Wilmanns Group, in collaboration with research groups from the Center for Experimental Medicine Institute of Tumor Biology and the Martini Clinic at the University Medical Center Hamburg-Eppendorf (UKE), as well as the Leibniz Institute on Aging - Fritz Lipmann Institute, has revealed a new mechanism