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Alkermes Buys Rodin Therapeutics to Bolster CNS Pipeline in $950 Million Deal

Biospace news - Mon, 11/18/2019 - 02:00
Under the terms of the deal, Alkermes is paying $100 million in cash upfront. Rodin will be eligible for future payments of up to $850 million based on clinical and regulatory milestones and sales thresholds.

Pfizer Wins FDA Approval for Biosimilar of AbbVie’s Humira

Biospace news - Mon, 11/18/2019 - 02:00
AbbVie’s blockbuster drug Humira just got another challenger to its share of the market in the United States when its patent expires in 2023.

Conducting a Post-Interview Self Evaluation

Biospace news - Mon, 11/18/2019 - 02:00
Is there any point in reliving a job interview you’ve just gone on? Can any good come from analyzing it and ruminating on it?

Novartis Cuts 150 Jobs As it Shifts Focus of Shanghai Facility to Drug Development

Biospace news - Mon, 11/18/2019 - 02:00
Three years after Novartis opened a $1 billion research & development facility in Shanghai, the company is shifting the focus of the site from drug discovery to commercial development.

Amgen and the Duke Clinical Research Institute announce initiation of first large-scale registry to evaluate real-world lipid management and the effectiveness of PCSK9 inhibitors

World Pharma News - Mon, 11/18/2019 - 02:00
Amgen (NASDAQ:AMGN) in collaboration with the Duke Clinical Research Institute (DCRI) announced plans to initiate the Cardiovascular Multi-dimensional Observational Investigation of the Use of PCSK9 inhibitors (cvMOBIUS) study - the first large-scale real-world study to assess lipid management and the impact of PCSK9 inhibitors on cardiovascular (CV) outcomes in clinical practice.

FDA approves first targeted therapy to treat patients with painful complication of sickle cell disease

World Pharma News - Fri, 11/15/2019 - 13:00
Today, the U.S. Food and Drug Administration approved Adakveo (crizanlizumab-tmca), a treatment to reduce the frequency of vaso-occlusive crisis - a common and painful complication of sickle cell disease that occurs when blood circulation is obstructed by sickled red blood cells - for patients age 16 years and older.

Bristol-Myers Squibb and Pfizer announce randomized, controlled trial to evaluate the effect of atrial fibrillation screening on health outcomes in older individuals

World Pharma News - Fri, 11/15/2019 - 11:00
The Bristol-Myers Squibb-Pfizer Alliance today announced the initiation of a new randomized, controlled study, GUARD-AF (ReducinG stroke by screening for UndiAgnosed atRial fibrillation in elderly inDividuals). The study seeks to determine if earlier detection of atrial fibrillation (AFib) through screening in previously undiagnosed men and women at least 70 years of age in the U.S. ultimately impacts the rate of stroke, compared to usual standard medical care.

Roche to Acquire Fibrosis-Focused Promedior for Up to $1.4 Billion

Biospace news - Fri, 11/15/2019 - 02:00
Under the terms of the agreement, Roche will make an upfront cash payment of $390 million, plus additional contingent payments of up to $1 billion based on the achievement of certain predetermined development, regulatory and commercial milestones.

BeiGene Announces FDA Approval of Brukinsa for Mantle Cell Lymphoma

Biospace news - Fri, 11/15/2019 - 02:00
It is the first BeiGene-discovered drug to be approved.

resTORbio Halts Respiratory Program for RTB101 After Phase III Failure

Biospace news - Fri, 11/15/2019 - 02:00
The company halted development of the drug for respiratory disease, but will continue to test it in other areas, including Parkinson’s disease. Shares plunged 74% in premarket trading at the news.

BioSpace Movers & Shakers, Nov. 15

Biospace news - Fri, 11/15/2019 - 02:00
Life sciences companies strengthen their leadership teams with this week's appointments.

Bayer and Dewpoint Therapeutics Ink $100 Million Research Partnership

Biospace news - Fri, 11/15/2019 - 02:00
The research pact will leverage Dewpoint’s biomolecular condensates technology platform and Bayer’s small molecule compound library to identify and develop new therapies for cardiovascular and gynecological diseases.

FUJIFILM Expands Texas Holdings with New Gene Therapy Center

Biospace news - Fri, 11/15/2019 - 02:00
FUJIFILM Corporation will invest 13 billion yen (about $120 million) to expand the company’s gene therapy business and establish a new Gene Therapy Innovation Center adjacent to its current facility in College Station, Texas and add about 100 jobs.

Research Roundup: New Molecule Slows Broad Range of Cancer Types and More

Biospace news - Fri, 11/15/2019 - 02:00
Every week there are numerous scientific studies published. Here’s a look at some of the more interesting ones.

Opinion: Personalized Medicine Is The Solution To Modern Cancer Treatment

Biospace news - Fri, 11/15/2019 - 02:00
People deserve a personalized approach in cancer treatment that considers their unique genetic traits and the latest medical research — this methodology stands a significantly increased chance of pushing back against the disease.

FDA Approves Shionogi’s cUTI Medicine Following Positive Advisory Support

Biospace news - Fri, 11/15/2019 - 02:00
The U.S. Food and Drug Administration approved Shionogi’s Fetroja as a treatment for adult patients with complicated urinary tract infections caused by a number of Gram-negative microorganisms.

Cover Letter Strategy Checklist

Biospace news - Fri, 11/15/2019 - 02:00
If you’re planning a cover letter or have one ready to send, take a stroll through this list to ensure strategic optimization.

Bayer and Dewpoint Therapeutics partner to research new treatments for cardiovascular and gynecological diseases

World Pharma News - Thu, 11/14/2019 - 13:00
Bayer and Dewpoint Therapeutics, a biotechnology company with sites in Boston and Dresden, Germany, today announced an option, research and license agreement worth up to USD 100 million. The partnership will leverage Dewpoint’s proprietary platform for biomolecular condensates and Bayer’s small molecule compound library to develop new treatments for cardiovascular and gynecological diseases.

A step closer to cancer precision medicine

World Pharma News - Thu, 11/14/2019 - 11:00
Researchers from the Faculty of Medicine and the Institute for Molecular Medicine (FIMM) at the University of Helsinki have developed a computational model, Combined Essentiality Scoring (CES) that enables accurate identification of essential genes in cancer cells for development of anti-cancer drugs.

Teva Changes Mind, Will Manufacture Childhood Chemotherapy Drug

Biospace news - Thu, 11/14/2019 - 02:00
The company discontinued development earlier this year, but a shortage prompted the reversal.