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Bristol-Myers Squibb’s Opdivo-Yervoy Combo Misses the Mark in Melanoma Study

Biospace news - Wed, 11/20/2019 - 02:00
The drug combination did not hit the co-primary endpoint of recurrence-free survival in patients whose tumors expressed PD-L1 greater than 1%.

New advances in the treatment of advanced lung cancer

World Pharma News - Tue, 11/19/2019 - 13:00
The University of Barcelona (UB) and Hospital Clínic de Barcelona collaborate with Boehringer Ingelheim Inc. to improve the efficiency of nintedanib, an antiangiogenic and antifibrotic drug, for the treatment of lung cancer. This public-private collaboration enabled researchers identify molecular mechanisms underlying the lack of efficiency of this drug in squamous cell carcinoma, a sub-type of non-small cell lung cancer, and the important role of smoking in this lack of effectivity.

Novartis announces new strategy to provide innovative medicines to more patients in sub-Saharan Africa

World Pharma News - Tue, 11/19/2019 - 11:00
Novartis announced a new strategy to broaden patient reach and availability of its portfolio of medicines in sub-Saharan Africa (SSA), which is home to the largest underserved patient population in the world. Novartis also aspires to be the partner of choice for governments and NGOs to strengthen healthcare systems across Africa.

Inflammatory Bowel Disease Insight Report: Current Therapies, Drug Pipeline and Outlook

Biospace news - Tue, 11/19/2019 - 02:00
Inflammatory bowel disease (IBD) is an umbrella term for two conditions, Crohn’s disease and ulcerative colitis, that are characterized by chronic inflammation of the gastrointestinal (GI) tract. This chronic and prolonged inflammation results in damage to the GI tract.

CRISPR Therapeutics and Vertex: Promising Gene Therapy Data for Sickle Cell Disease and Beta Thal...

Biospace news - Tue, 11/19/2019 - 02:00
CRISPR Therapeutics and Vertex Pharmaceuticals announced positive interim data from the first two patients in the companies’ ongoing Phase I/II clinical trials of its CRISPR/Cas9 gene-editing therapy CTX001.

Martin Shkreli Will Continue to Serve Prison Sentence After Supreme Court Denies Appeal

Biospace news - Tue, 11/19/2019 - 02:00
On Monday, the U.S. Supreme Court refused to overturn his seven-year conviction for securities fraud.

Myovant's Prostate Cancer Drug Ready to Submit to FDA Following Positive Trial Results

Biospace news - Tue, 11/19/2019 - 02:00
Myovant announced that its Phase III HERO trial relugolix met its primary endpoint and six key secondary endpoints in advanced prostate cancer.

'A Clever Bit of Chemistry': NuCana CEO Speaks on Company's Biliary Tract Cancer Drug

Biospace news - Tue, 11/19/2019 - 02:00
If successful, the CEO told BioSpace in an exclusive interview that Acelarin will break the glass ceiling as the first FDA-approved treatment for biliary tract cancer.

Up-and-Coming Female Powerhouses of Biotech

Biospace news - Tue, 11/19/2019 - 02:00
Balancing slim chances with a drive for success, each of these women beat the biotech odds.

4 Habits That Are Killing Your Productivity at Work

Biospace news - Tue, 11/19/2019 - 02:00
We challenge you to stop doing these things next week and see how your work productivity skyrockets.

Preclinical Research Shows Promise For New Approach to Treating Progeria

Biospace news - Tue, 11/19/2019 - 02:00
New research is shedding light on a possible new approach to treating the rare and fatal premature aging syndrome, progeria.

A Vicious Cycle: “There Are No Women in the Boardroom Because There Are No Women in the Boardroom”

Biospace news - Tue, 11/19/2019 - 02:00
We interviewed Patti Rossman, president of Globiox and co-founder of the Life Science Women’s Conference. Patti shared her insights from a diverse career with large organizations and in consulting.

Amidst Novartis Takeover Rumors, The Medicines Company Announces Positive Cholesterol Data

Biospace news - Tue, 11/19/2019 - 02:00
Amidst rumors that Novartis might be interested in an acquisition, The Medicines Company announced data from ORION-10, the second of three 19-month Phase III trials of inclisiran for lowering cholesterol.

Statins not associated with memory or cognition decline in elderly, may be protective in some patients

World Pharma News - Mon, 11/18/2019 - 13:00
Given consumer concern that statins may be associated with memory or cognitive decline, a new study published today in the Journal of the American College of Cardiology may offer reassurance, as no difference was found in the rate of memory or cognitive decline of elderly statin-users compared to never-users.

FDA Approves Novartis' Adakveo for Pain Events Associated with Sickle Cell Disease

Biospace news - Mon, 11/18/2019 - 02:00
“The approval of Adakveo marks a new era in the treatment of sickle cell disease, a genetic condition that places an extraordinary burden of unpredictable pain crises on patients and their families,” said Susanne Schaffert, president of Novartis Oncology.

Dicerna Partners with Novo Nordisk on 30 Liver Disease Targets

Biospace news - Mon, 11/18/2019 - 02:00
They will leverage Dicerna’s GalXC RNAi technology platform to explore more than 30 liver cell targets.

Heart Failure Drug Developed by Merck and Bayer Meets Endpoints in Phase III Trial

Biospace news - Mon, 11/18/2019 - 02:00
The results of the Phase III VICTORIA trial set up the potential for the companies to seek regulatory approval for vericiguat.

Top Priorities for Women When It Comes to Life Sciences Employers

Biospace news - Mon, 11/18/2019 - 02:00
We interviewed three women with thriving life sciences careers to dive deeper into what women prioritize in an employer.

Clinical Catch-Up: November 11-15

Biospace news - Mon, 11/18/2019 - 02:00
It was a busy week for clinical trial announcements. Here’s a look.

Top 10 Biotech Bay Companies by Revenue

Biospace news - Mon, 11/18/2019 - 02:00
The companies included on this list are the top ten companies headquartered in Biotech Bay based on 2018 revenue.